As a dedicated OneNote user I am accustomed to its screen clipping function for more than ten years now. Its long-time shortcut was Windows + S until it recently changed to Windows + Shift + S, the former being donated to Windows’ 8.X/10 search functionality.
I wanted to get back the old shortcut to OneNote and did a little research on the web. So here is the receipt that worked for me and probably most users. Credits got to this blog: http://superuser.com/questions/947802/windows-10-shortcuts-onenote-vs-cortana
You need to copy and paste the text below for into a .REG file and run, or you follow manually the path and make the two registry changes there. Be careful though. And don’t forget to log out and in again for this to take effect.
Windows Registry Editor Version 5.00
[HKEY_CURRENT_USER\Software\Microsoft\Office\16.0\OneNote\Options\Other]
"ScreenClippingShortcutKey"=dword:00000053
[HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\Advanced]
"DisabledHotkeys"="s"
For the ones doing this manually: the ScreenClippingShortcutKey value is of type REG_DWORD 32-bit and the DisabledHotkeys value is of type REG_SZ.
By the way you can disable more shortcuts if you like. For example, "DisabledHotkeys"="si" will disable the shortcuts for both Search and Settings charms.